Title:
被検物質の検出用ポリマーコーティングを含む熱電対および関連方法
Document Type and Number:
Japanese Patent JP6970412
Kind Code:
B2
Abstract:
A device (200) for detecting an analyte (132) includes a thermocouple (210) coated with an assay polymer (214). The assay polymer is formulated to bind to the analyte, and a heat transfer property of the assay polymer varies responsive to an amount of the analyte bound thereto. A method of forming a sensor includes coating a thermocouple with an assay polymer. A method for detecting an analyte includes passing a liquid containing an analyte adjacent a thermocouple coated with an assay polymer, binding an analyte to the assay polymer, detecting a temperature of the thermocouple, and calculating a concentration of the analyte in the liquid based at least in part on the heat transfer property of the assay polymer.
Inventors:
Frinsfen, Fan, Barth Robert Nicolas
Craig Thomas Jean
Craig Thomas Jean
Application Number:
JP2018553456A
Publication Date:
November 24, 2021
Filing Date:
November 03, 2016
Export Citation:
Assignee:
UNIVERSITEIT MAASTRICHT
ACADEMISCH ZIEKENHUIS MAASTRICHT
ACADEMISCH ZIEKENHUIS MAASTRICHT
International Classes:
G01N25/18; C12Q1/68; G01N27/00
Domestic Patent References:
| JP2009097919A | ||||
| JP61212750A | ||||
| JP6294763A |
Foreign References:
| US20140011198 | ||||
| US20140242605 |
Other References:
Gideon Wackers,Array Formatting of the Heat-Transfer Method (HTM) for the Detection of Small Organic Molecules by Molecularly Imprinted Polymers,Sensors,2014年06月20日,14,11016-11030,doi:10.3390/s140611016
Kasper Eersels,Selective Identification of Macrophages and Cancer Cells Based onThermal Transport through Surface-Imprinted Polymer Layers,ACS Appl. Mater. Interfaces,ACS publications,2013年,5,7258-7267,dx.doi.org/10.1021/am401605d
M. Peeters & P.,Heat-transfer-based detection of L-nicotine, histamine, and serotonin using molecularly imprinted polymers as biomimetic receptors,Anal Bioanal Chem,Springer,2013年05月18日,405,6453-6460,DOI 10.1007/s00216-013-7024-9
Kasper Eersels,Selective Identification of Macrophages and Cancer Cells Based onThermal Transport through Surface-Imprinted Polymer Layers,ACS Appl. Mater. Interfaces,ACS publications,2013年,5,7258-7267,dx.doi.org/10.1021/am401605d
M. Peeters & P.,Heat-transfer-based detection of L-nicotine, histamine, and serotonin using molecularly imprinted polymers as biomimetic receptors,Anal Bioanal Chem,Springer,2013年05月18日,405,6453-6460,DOI 10.1007/s00216-013-7024-9
Attorney, Agent or Firm:
Sakaki Morishita
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