Title:
ロイコトリエンA4加水分解酵素の調節因子としてのチアゾロピリジン-2-イルオキシ-フェニル及びチアゾロピラジン-2-イルオキシ-フェニルアミン
Document Type and Number:
Japanese Patent JP2011516571
Kind Code:
A
Abstract:
Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.
Inventors:
Bakani, Genesis M
Brodini, Diego
Chiyun, Eugene Wye
Crobian, christa sea
Den, shea off
Foley, Anne M
Gomez, Laurent
Grice, Cielille A
Kearney, Aaron M
Laundry-Vail, Adrienne M
Lee-Deutra, Alice
Liam, Jimmy Tay
Lofner, Suzanne
Mani, Nylacanda S
Sant'Eylan, Alejandro, Giunia
Suppy, Kiaslean Sea
Sepak, Kia
Tanith, Virginia M
Wyke Bolt, Alba Tay
Wiener, JiJon JM
Ginzer, hartmut
Brodini, Diego
Chiyun, Eugene Wye
Crobian, christa sea
Den, shea off
Foley, Anne M
Gomez, Laurent
Grice, Cielille A
Kearney, Aaron M
Laundry-Vail, Adrienne M
Lee-Deutra, Alice
Liam, Jimmy Tay
Lofner, Suzanne
Mani, Nylacanda S
Sant'Eylan, Alejandro, Giunia
Suppy, Kiaslean Sea
Sepak, Kia
Tanith, Virginia M
Wyke Bolt, Alba Tay
Wiener, JiJon JM
Ginzer, hartmut
Application Number:
JP2011504176A
Publication Date:
May 26, 2011
Filing Date:
April 09, 2009
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D513/04; A61K31/437; A61K31/438; A61K31/439; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/496; A61K31/4985; A61K31/4995; A61K31/506; A61K31/5377; A61K31/55; A61K31/5513; A61P1/04; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P37/08; A61P43/00; C07D519/00; C07B53/00; C07B61/00
Domestic Patent References:
| JPS5865297A | 1983-04-18 | |||
| JP2006525997A | 2006-11-16 | |||
| JP2011502150A | 2011-01-20 | |||
| JPH05213911A | 1993-08-24 | |||
| JPH09507080A | 1997-07-15 |
Foreign References:
| US20040198768A1 | 2004-10-07 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office