チオアミド化合物、チオアミド化合物の製造方法、［（４Ｒ，６Ｒ）−６−アミノエチル−１，３−ジオキサン−４−イル］アセテート誘導体の製造方法、及びアトルバスタチンの製造方法

Title:

Document Type and Number:

Japanese Patent JP5705580

Kind Code:

B2

Abstract:

A thioamide compound represented by the following general formula (1): wherein, in the general formula (1), R 1 represents one of -OR 11 and -NR 12 R 13 ; R 2 and R 3 each independently represent one of a protecting group of an amide group and a hydrogen atom; the R 11 represents one of a protecting group of a hydroxyl group and a hydrogen atom; and the R 12 and R 13 each independently represent one of a protecting group of an amino group and a hydrogen atom, where the R 12 and R 13 may together form a protecting group having a cyclic structure.

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Inventors:

Masakatsu Shibasaki
Naoya Kumagai

Application Number:

JP2011035006A

Publication Date:

April 22, 2015

Filing Date:

February 21, 2011

Export Citation:

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Assignee:

Institute for Microbial Chemistry

International Classes:

C07C327/42; A61K31/40; A61P3/06; A61P13/08; A61P19/10; A61P25/28; C07D207/34; C07F7/18

Other References:

Journal of the American Chemical Society,2009年,Vol.131, No.51,p.18244-5
日本薬学会第130年会要旨集2,2010年 3月 5日,第122頁,講演番号:30TF-am07
Tetrahedron,2011年,Vol.67,p.6539-46,Available online:2011.06.02
日本薬学会第131年会要旨集2,2011年 3月 5日,第172頁,講演番号:31P-0202

Attorney, Agent or Firm:

Koichi Hirota
Yoshihiro Nagare
Naoko Matsuda

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