THIOETHER SUBSTITUTED IMIDAZOQUINOLINE

Japanese Patent JP2010031024

A

To provide a compound by attempting to identify compounds that are useful as immune response modifiers to find compounds that have the ability to modulate the immune response by induction of cytokine biosynthesis or other mechanisms.

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

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BONK JASON D
DELLARIA JOSEPH F JR
MERRILL BRYON A
RADMER MATTHEW R

JP2009223107A

February 12, 2010

September 28, 2009

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THREE M INNOVATIVE PROPERTIES

C07D471/04; A61K31/437; A61K31/4745; A61K31/506; A61P1/16; A61P7/00; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P17/02; A61P17/12; A61P17/14; A61P25/00; A61P31/02; A61P31/04; A61P31/06; A61P31/08; A61P31/10; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P33/00; A61P33/02; A61P35/00; A61P35/02; A61P37/02; A61P37/08; A61P43/00

JPH09500628A	1997-01-21
JPH06510299A	1994-11-17
JPH06504789A	1994-06-02
JP2001502699A	2001-02-27
JP2001525411A	2001-12-11

WO2000076518A1

2000-12-21

Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Nagasaka Tomoyasu
Yoshihiro Kobayashi
Atsushi Ebiya

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