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Title:
プロスタグランジンI2アンタゴニストとしてのチオフェニルアミノイミダゾリン類
Document Type and Number:
Japanese Patent JP2009513521
Kind Code:
A
Abstract:
Methods for treatment of IP antagonist mediated diseases or conditions by administration to a subject in need thereof a compound of formula (I) wherein R1, R2, A and X are as defined herein. Also disclosed are compounds and related compositions.

Inventors:
Bray, Case Roger
Clark, Robin Douglas
Jahan Gear, Alam
Application Number:
JP2006518128A
Publication Date:
April 02, 2009
Filing Date:
July 07, 2004
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D211/72; A61K31/155; A61K31/4168; A61K31/4402; A61P7/10; A61P9/02; A61P11/00; A61P11/06; A61P13/02; A61P13/08; A61P13/10; A61P19/02; A61P25/04; A61P25/06; A61P27/02; A61P27/14; A61P29/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P37/08; A61P41/00; A61P43/00; C07D233/46; C07D233/50; C07D239/14; C07D243/08; C07D295/096; C07D401/12; C07D405/12; C07D487/04
Domestic Patent References:
JPS5463080A1979-05-21
JP2006525254A2006-11-09
JPS55136266A1980-10-23
JPH11140057A1999-05-25
Foreign References:
WO2002040453A12002-05-23
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda