Title:
トロンビンインヒビター
Document Type and Number:
Japanese Patent JP5699393
Kind Code:
B2
Abstract:
The invention relates to thrombin inhibitors derived from the salivary glands of haematophagous arthropods and in particular to bivalent and trivalent thrombin inhibitors that act by interacting with thrombin at two or three different sites.
Inventors:
Kazymirova, Maria
Kini, Earl. Manjunasa
Ko, Cho
Kini, Earl. Manjunasa
Ko, Cho
Application Number:
JP2010512807A
Publication Date:
April 08, 2015
Filing Date:
June 18, 2008
Export Citation:
Assignee:
National University of Singapore
International Classes:
C12N15/09; A61K38/00; A61K48/00; A61P7/02; A61P43/00; C07K7/08; C07K14/81; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/99; C12P21/02; C12Q1/37
Foreign References:
| WO2003091284A1 |
Other References:
Am. Heart J. 2005, 149(1 Suppl.), pp.S43-53
J. Biol. Chem., 2007 Oct 5, 282(40), pp.29101-29113, Epub 2007 Aug 7
J. Biol. Chem., 2007 Oct 5, 282(40), pp.29101-29113, Epub 2007 Aug 7
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Yumi Naito
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Yumi Naito