Title:
Ｔｉｅ２活性化剤、血管新生抑制剤、及び経口用組成物
Document Type and Number:
Japanese Patent JP7165427
Kind Code:
B2
Abstract:
To provide a Tie2 activator, an antiangiogenic agent, an agent for blood vessel maturation, a blood vessel normalizing agent, and a blood vessel stabilizing agent, and food and drink, having excellent Tie2 activation action, antiangiogenic action, blood vessel maturation action, blood vessel normalization action, and blood vessel stabilization action, and high safety.SOLUTION: The present disclosure provides a Tie2 activator, an agent for blood vessel maturation, and blood vessel stabilizing agent, and food and drink, comprising at least one of water extract of the rhizome part of Butcher's broom, hydrophilic solvent extract thereof, and water- and hydrophilic solvent-mixed solvent extract, as an active ingredient.SELECTED DRAWING: None
Inventors:
Nobuaki Oto
Application Number:
JP2020139987A
Publication Date:
November 04, 2022
Filing Date:
August 21, 2020
Export Citation:
Assignee:
Maruzen Pharmaceutical Co., Ltd.
International Classes:
A61K36/48; A61K35/56; A61K35/618; A61K36/00; A61K36/16; A61K36/18; A61K36/28; A61K36/282; A61K36/52; A61K36/61; A61K36/72; A61K36/73; A61K36/732; A61K36/81; A61K36/815; A61K36/896; A61K36/8968; A61P9/00; A61P9/14; A61P43/00
Domestic Patent References:
| JP2010105922A | ||||
| JP2004075640A | ||||
| JP2000239177A |
Foreign References:
| KR1020110124916A | ||||
| CN101554442A |
Other References:
Int J Pharm,2010年03月31日,Vol.6, No.3,pp.216-223
Evidence-Based Complementary and Alternative Medicine, 2011.06.08, Vol.2011, Article No.219069, pp.1-8
J. Smooth Muscle Res., 2008, Vol.44, No.6, pp.217-229
Evidence-Based Complementary and Alternative Medicine, 2011.06.08, Vol.2011, Article No.219069, pp.1-8
J. Smooth Muscle Res., 2008, Vol.44, No.6, pp.217-229
Attorney, Agent or Firm:
Tadashige Ito
Tadahiko Ito
Koichi Hirota
Yoshihiro Ryu
Tadahiko Ito
Koichi Hirota
Yoshihiro Ryu