組織拒絶反応 - University Court of the University of Glasgow

Title:

組織拒絶反応

Document Type and Number:

Japanese Patent JP2005514960

Kind Code:

A

Abstract:

Methods and materials for treating tissues to reduce the risk of transplant rejection are described, along with methods for determining the risk of rejection of transplants. The level of expression of various senescence-associated genes, such as G22P1, XRCC5, hPOT1 and SIRT2 and homologues or analogues thereof, is considered indicative of tissue rejection, and their levels may be modulated to reduce the risk of rejection. The tissue are preferably renal tissues.

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Inventors:

Paul G Shields

Application Number:

JP2003562334A

Publication Date:

May 26, 2005

Filing Date:

January 16, 2003

Export Citation:

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Assignee:

University Court of the University of Glasgow

International Classes:

C12N15/09; A61K38/13; A61K38/16; A61P13/12; A61P37/06; A61P41/00; A61P43/00; C12N5/07; C12N5/071; C12Q1/02; C12Q1/40; C12Q1/68; C12Q1/6881; (IPC1-7): C12Q1/68; A61K38/16; A61P13/12; A61P37/06; A61P41/00; A61P43/00; C12N5/06; C12N15/09; C12Q1/02; C12Q1/40

Attorney, Agent or Firm:

Masatake Shiga
Takashi Watanabe
Masakazu Aoyama
Yasuhiko Murayama
Shinya Mitsuhiro

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