Title:
【発明の名称】10―ディアザアミノプテリン:新規関節炎緩和剤
Document Type and Number:
Japanese Patent JPH04506082
Kind Code:
A
Abstract:
A double blind clinical trial of 10-deazaaminopterin versus the antirheumatoid drug methotrexate (MTX) established that 10-deazaaminopterin, in addition to being at least equally effective as methotrexate in all respects in ameliorating rheumatoid arthritis in humans, it is superior to methotrexate in controlling pain and joint stiffness and in improving grip strength. In accordance with this invention 10-deazaaminopterin is claimed as a more effective disease modifying arthritis remittive drug for the treatment of rheumatoid arthritis in humans.
Inventors:
Nea, Mad Haven, Gee
Arachon, Gracila
Castaneda, Oswald
Coupman, william, jay
Kulmdijk, Carlos, El
Arachon, Gracila
Castaneda, Oswald
Coupman, william, jay
Kulmdijk, Carlos, El
Application Number:
JP50665791A
Publication Date:
October 22, 1992
Filing Date:
March 25, 1991
Export Citation:
Assignee:
Nea, Mad Haven, Gee
International Classes:
A61K31/505; A61K31/519; A61P29/00; C07D475/08; (IPC1-7): A61K31/505; C07D475/08
Attorney, Agent or Firm:
Makoto Kanesaka (2 outside)