Title:
【発明の名称】3,18‐ジヒドロキシ‐9,13‐エポキシラブダン誘導体,それらの調製方法およびそれらに基づく止血医薬製剤
Document Type and Number:
Japanese Patent JPH03502456
Kind Code:
A
Abstract:
New compositions which are derivatives of 3,18-dihydroxy-9,13-epoxylabdane of general formula (I), where R = (a); (b). A method of obtaining said derivatives of 3,18-dihydroxy-9,13-epoxylabdane consists in subjecting the 3,18-dihydroxy-9,13-epoxylabdane to the dehydration in the medium of an organic solvent at the latter's boiling temperatures in the presence of a catalyst and in subsequently extracting the desired product. The proposed compositions have hemostatic properties. A hemostatic pharmaceutical preparation comprises, as an active component, the trihydrate of the sodium salt of 3,16,18-trihydroxy-9,13-epoxylabdane-15-acid.
Inventors:
Zainut Dinov, Umarjan Naslut Dinovic
Nurumatova, Mubarak Pirmatovna
Aslanov, Hakim
Sadikov, Abid
Abdulrahmanov, tile
Nasirov, Sanjar al-Hidarovich
Islamov, Rahim
Danilchuk, Dmitri Nikolaevich
Jankowski, Boris Andreevich
Zaharov, Badim Paflovich
Nurumatova, Mubarak Pirmatovna
Aslanov, Hakim
Sadikov, Abid
Abdulrahmanov, tile
Nasirov, Sanjar al-Hidarovich
Islamov, Rahim
Danilchuk, Dmitri Nikolaevich
Jankowski, Boris Andreevich
Zaharov, Badim Paflovich
Application Number:
JP50384189A
Publication Date:
June 06, 1991
Filing Date:
November 30, 1988
Export Citation:
Assignee:
Tashkentski Gosdarst Benni Université Imeni B. E. Renina
Institute Bio Organicheskoy Himi Academia Nauk Uzbekskoy SLS
Institute Bio Organicheskoy Himi Academia Nauk Uzbekskoy SLS
International Classes:
A61K9/08; A61K31/19; A61K31/34; A61K31/35; A61K31/365; A61P7/04; C07D307/12; C07D307/94; C07D311/92; C07D311/96; C07D493/10; (IPC1-7): C07D307/94; A61K31/34; A61K31/365; C07D493/10
Attorney, Agent or Firm:
Aoki Akira (3 outside)