Title:
【発明の名称】3-エピビタミンD2化合物及びその使用法
Document Type and Number:
Japanese Patent JP2002506429
Kind Code:
A
Abstract:
Novel 3-epi vitamin D2 compounds having the orientation of the substituent attached to the carbon at position 3 of the A-ring of vitamin D2 inverted from a beta ( beta ) to an alpha ( alpha ) configuration are described. These compounds were first identified as metabolites of vitamin D2 produced via a tissue-specific metabolic pathway which catalyzes the 3- beta -hydroxy epimerization of vitamin D2 compounds. The 3-epi vitamin D2 compounds of the present invention can be used as substitutes for natural and synthetic vitamin D.
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Inventors:
Lady Sataya Narayana Gee.
Application Number:
JP54963198A
Publication Date:
February 26, 2002
Filing Date:
May 15, 1998
Export Citation:
Assignee:
Women and Infants Hospital
International Classes:
A61K31/59; A61K31/592; A61P3/00; A61P5/18; A61P13/12; A61P19/08; A61P19/10; A61P43/00; C07C401/00; (IPC1-7): C07C401/00; A61K31/59; A61P3/00; A61P5/18; A61P13/12; A61P19/08; A61P19/10; A61P43/00
Attorney, Agent or Firm:
Yoshiki Ishida (1 person outside)