Title:
【発明の名称】5員複素環化合物、それらを有効成分として含有する薬剤
Document Type and Number:
Japanese Patent JPH10506892
Kind Code:
A
Abstract:
This invention is related to: (1) an inhibitory agent on 5 alpha -reductase which comprises a five membered heterocyclic compound of formula (Ia), and non-toxic salts thereof as active ingredient; (2) a five membered heterocyclic compound of formula (Ib), and non-toxic salts thereof; (3) process for the preparation of a five membered heterocyclic ring compound of formula (Ib) and non-toxic salts thereof. The compounds of formula (Ia) are useful for the prevention and treatment of diseases induced by the excess generation of dihydrotestosterone in mammals, for example, alopecia (androgenic alopecia), acnes, hypertrophy of prostate and prostatic cancer.
Inventors:
Lee Sung Jai
Takuya Seko
Fireson Menton Rogers
Circa Jagadis Chandra
Khao Charles Xian
Takuya Seko
Fireson Menton Rogers
Circa Jagadis Chandra
Khao Charles Xian
Application Number:
JP51186796A
Publication Date:
July 07, 1998
Filing Date:
September 27, 1995
Export Citation:
Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
A61K31/34; A61K31/341; A61K31/381; A61K31/40; A61K31/4025; A61K31/4035; A61K31/4164; A61K31/4172; A61K31/4178; A61K31/443; A61K31/4436; A61K31/4439; A61P17/00; A61P43/00; C07D207/333; C07D207/337; C07D233/54; C07D233/64; C07D263/32; C07D277/20; C07D277/30; C07D307/54; C07D333/24; C07D403/10; C07D405/06; C07D409/06; C07D409/10; C07D207/32; (IPC1-7): C07D207/333; A61K31/34; A61K31/40; C07D233/64; C07D263/32; C07D277/30; C07D307/54; C07D333/24; C07D403/10; C07D405/06; C07D409/06; C07D409/10
Attorney, Agent or Firm:
Kunihisa Oya (1 outside)