Title:
【発明の名称】7‐ハロ‐および7β,8β‐メタノ‐タキソール、抗新生物剤としての使用およびそれを含有する医薬組成物
Document Type and Number:
Japanese Patent JP3441458
Kind Code:
B2
Abstract:
This invention provides 7-deoxy-taxol analogs of Formula I: The compounds of Formula I (including II and III) are useful for the same cancers for which taxol has been shown active, including human ovarian cancer, breast cancer, and malignant melanoma as well as lung cancer, gastric cancer, colon cancer, head and neck cancer, and leukemia.
Inventors:
Hester, jackson bee, junior
Roy A. Johnson
Kelly, robert sey
Midi, Eldon Zee
Skullnick, Herbie Eye
Roy A. Johnson
Kelly, robert sey
Midi, Eldon Zee
Skullnick, Herbie Eye
Application Number:
JP51431294A
Publication Date:
September 02, 2003
Filing Date:
December 13, 1993
Export Citation:
Assignee:
PHARMACIA&UPJOHN COMPANY
International Classes:
A61K31/335; A61K31/337; A61P35/00; C07D263/06; C07D305/14; C07D405/12; C07D407/12; C07D409/12; C07D413/12; C07F7/18; (IPC1-7): C07D305/14; A61K31/335; A61P35/00
Other References:
【文献】国際公開92/09589(WO,A1)
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)