Title:
【発明の名称】アミノ酸誘導体
Document Type and Number:
Japanese Patent JP3361836
Kind Code:
B2
Abstract:
Constitution: an amino acid derivative represented by the general formula (I): R<1>NH-CH(R<2>)-CONH-A-ONO2 and a pharmacologically acceptable salt thereof, wherein R<1> represents hydrogen, C1-C7 alkanoyl, C1-C6 alkoxycarbonyl, C6-C10 arylcarbonyl, C7-C13 aralkylcarbonyl, C7-C13 aralkyloxycarbonyl, or 5- or 6-membered heteroarylcarbonyl; R<2> represents substituted C1-C6 alkyl; and A represents C2-C5 alkylene. Effect: this compound is excellent in a collateral vessel dilator activity and an antianginal activity, and hence useful as an antianginal drug.
Inventors:
Sadao Ishihara
Fujio Saito
Takao Yoshioka
Hiroyuki Koike
Shigeki Miyake
Hiroshi Mizuno
Fujio Saito
Takao Yoshioka
Hiroyuki Koike
Shigeki Miyake
Hiroshi Mizuno
Application Number:
JP16867592A
Publication Date:
January 07, 2003
Filing Date:
June 26, 1992
Export Citation:
Assignee:
Sankyo Co., Ltd.
International Classes:
A61K31/40; A61K31/403; A61K31/404; A61K31/41; A61K31/425; A61K31/426; A61K31/465; A61P9/08; A61P9/10; C07C237/08; C07C237/12; C07C237/20; C07C237/22; C07C237/34; C07C271/22; C07C323/60; C07C327/06; C07C327/16; C07C327/34; C07C329/06; C07D209/18; C07D209/20; C07D213/32; C07D213/81; C07D213/82; C07D213/83; C07D233/54; C07D233/64; A61K31/27; C07D277/20; C07D277/30; C07D307/68; C07D309/08; C07D317/38; C07D333/38; (IPC1-7): C07C237/08; C07C237/20; C07C237/22; C07C237/34; C07C271/22; C07C323/60; C07C327/06; C07C327/16; C07C329/06; C07D209/20; C07D213/32; C07D213/81; C07D213/82; C07D213/83; C07D233/54; C07D233/64; C07D277/30; C07D307/68; C07D309/08; C07D317/38; C07D333/38
Domestic Patent References:
| JP2169558A |
Attorney, Agent or Firm:
Akio Ohno (1 outside)