Title:
【発明の名称】抗菌性胆汁酸誘導体
Document Type and Number:
Japanese Patent JPH05508392
Kind Code:
A
Abstract:
PCT No. PCT/GB91/00710 Sec. 371 Date Oct. 27, 1992 Sec. 102(e) Date Oct. 27, 1992 PCT Filed May 3, 1991 PCT Pub. No. WO91/16898 PCT Pub. Date Nov. 14, 1991.Compounds of the general formula (7): (* CHEMICAL STRUCTURE *) (7) wherein X is a hydrogen atom or a hydroxyl group, Y is a hydrogen atom or a hydroxyl group and at least one of X and Y is a hydroxyl group and Z is a hydroxyl group or a methylol (-CH2OH) group, have anti-fungal activity, especially against organisms selected from Candida spp. and the athlete's foot/ringworm organisms Trichophyton mentagrophytes and Microsporum audonii. Compounds in which Z is a methylol (-CH2OH) group are claimed per se.
Inventors:
Marples, Brian Arthur
Stretton, Reginald John
Stretton, Reginald John
Application Number:
JP50851691A
Publication Date:
November 25, 1993
Filing Date:
May 03, 1991
Export Citation:
Assignee:
Loughborough University of Technology
International Classes:
A61K31/575; A61P31/04; C07J9/00; (IPC1-7): A61K31/575; C07J9/00
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)