Title:
【発明の名称】MCA16‐88によって認識される抗原
Document Type and Number:
Japanese Patent JP3081208
Kind Code:
B2
Abstract:
The present invention comprises the epitope recognized by the human monoclonal antibody 16-88, the human tumor antigen containing this epitope, which we have identified, isolated and characterized, and anti-idiotypic antibodies to human MCA 16-88, which comprise the same epitope. The invention also relates to the use of antibodies to the antigen containing this epitope for diagnosis and monitoring of treatment of cancer and to the use of this antigen in the preparation of vaccines to elicit an immune response similar to that obtained against tumor cells containing this epitope.
Inventors:
Pomato, Nicholas
Boss, Evo S
Haspel, Martin Victor
Hannah, Michael Gioji Giunia
Berman, Michael Lou
Boss, Evo S
Haspel, Martin Victor
Hannah, Michael Gioji Giunia
Berman, Michael Lou
Application Number:
JP50598388A
Publication Date:
August 28, 2000
Filing Date:
July 01, 1988
Export Citation:
Assignee:
Akzo Nva
International Classes:
G01N33/574; A61K39/00; A61K39/395; A61P35/00; C07K1/22; C07K14/435; C07K14/705; C07K16/00; C07K16/30; C07K16/42; C12N5/02; C12N5/10; C12N15/09; C12P21/00; C12P21/08; G01N33/531; G01N33/577; C12R1/91; (IPC1-7): C12N5/10; A61K39/00; A61K39/395; C07K14/705; C07K16/30
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)