Title:
【発明の名称】タンパク質キナーゼC-シータ発現のアンチセンスモジュレーション
Document Type and Number:
Japanese Patent JP2003512079
Kind Code:
A
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of Protein kinase C-theta. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Protein kinase C-theta. Methods of using these compounds for modulation of Protein kinase C-theta expression and for treatment of diseases associated with expression of Protein kinase C-theta are provided.
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Inventors:
Bennett, Sea Frank
Kausart, Rex M
Kausart, Rex M
Application Number:
JP2001533186A
Publication Date:
April 02, 2003
Filing Date:
October 20, 2000
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
C12N15/00; A61K9/107; A61K31/7088; A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P3/10; A61P17/02; A61P31/18; A61P35/00; C07H19/06; C07H19/10; C07H19/16; C07H19/20; C07H21/00; C07H21/02; C12N9/99; C12N15/113; A61K38/00; C12Q1/68; (IPC1-7): C12N15/00; A61K9/107; A61K31/7088; A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P3/10; A61P17/02; A61P31/18; A61P35/00; C07H21/02; C12N9/99
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)