Title:
【発明の名称】金属ポルフィリン誘導体、その製造方法、治療法への適用及びハイブリッド分子製造での使用
Document Type and Number:
Japanese Patent JPH03504725
Kind Code:
A
Abstract:
PCT No. PCT/FR89/00273 Sec. 371 Date Nov. 28, 1990 Sec. 102(e) Date Nov. 28, 1990 PCT Filed Jun. 2, 1989 PCT Pub. No. WO89/12049 PCT Pub. Date Dec. 14, 1989.Metalloporphyrin derivatives of the formula I in which A and B each represents: and Z+ represents N+-R1 or C-N+R1R2R3, R1 being C1-C10 linear or branched aliphatic, and R2 and R3 each being hydrogen or C1-C10 linear or branched aliphatic, R represents NH2, OH, COOH or -N(R1)3 group or a halogen, n is 0 or an integer from 1 to 10, the corresponding alkylene group being either linear or branched, M represents Fe or Mn, and X represents the anion of a pharmaceutically acceptable carboxylic acid, m being an integer from 1 to 5, and Y represents a bond or a -O-, -CO- or -CONH- radical. The compounds have antitumoral and antiviral utility.
Inventors:
Mounier, Bernard
Etouma-Mogadan, Guitar
Dan, Li
Black and white
Etouma-Mogadan, Guitar
Dan, Li
Black and white
Application Number:
JP50669489A
Publication Date:
October 17, 1991
Filing Date:
June 02, 1989
Export Citation:
Assignee:
Center Nacional Dou la Lucier Ciuyan Caytei Fique (S.N.A.L.S)
International Classes:
A61K31/40; A61K41/00; A61P35/00; C07D487/22; C07F3/06; C07F13/00; C07F15/02; C07F15/04; C07F19/00; (IPC1-7): A61K31/40; C07D487/22
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)