Title:
【発明の名称】細菌性カルボキシペプチダーゼCPG2変種と遺伝子指令酵素プロドラッグ療法におけるその使用
Document Type and Number:
Japanese Patent JP2003532425
Kind Code:
A
Abstract:
The present invention relates to bacterial carboxypeptidases for use in gene directed prodrug therapy, in particular for use in the treatment of disease, including tumors. Specifically, the invention relates to modified bacterial carboxypeptidases which have enhanced catalytic activity.
Inventors:
Springer, Caroline, Joy
Malais, Richard, Marcolm
Robert Spooner
Malais, Richard, Marcolm
Robert Spooner
Application Number:
JP2001582549A
Publication Date:
November 05, 2003
Filing Date:
May 04, 2001
Export Citation:
Assignee:
Cancer Research Technology Limited
International Classes:
C12N15/09; A61K31/131; A61K35/76; A61K45/00; A61K47/48; A61K48/00; A61P35/00; A61P43/00; C12N9/48; C12N9/52; C12N15/57; C12N15/87; C12R1/38; (IPC1-7): C12N15/09; A61K31/131; A61K35/76; A61K45/00; A61K48/00; A61P35/00; A61P43/00; C12N9/52
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)