Title:
【発明の名称】ベータ―ラクタム誘導体
Document Type and Number:
Japanese Patent JP2840286
Kind Code:
B2
Abstract:
There are provided compounds of the formula Ia and Ib wherein A is hydrogen atom or an organic residue, R<1> is halogen atom, or an organic group, R<2> is hydrogen or halogen atom, C1-C4 alkyl or alkoxy group R<3> is hydrogen atom, C1-C4 alkyl or alkoxy group, benzyl or a methylene group and R4 is an organic residue. Said derivatives (Ia) and (Ib) are endowed with elastase inhibitory activity. A two-step process for their preparation starting from the corresponding 4-carboxy cephem or 3-carboxy penam is also provided.
Inventors:
PIERURUIJI BITSUSORIINO
MARUKO ARUPEJAANI
ETSUTOORE PEROONE
PIEERUJOZETSUPE ORETSUTSUI
JUZETSUPE KATSUSHINETSURI
JOBANNI FURANCHESUKI
MARUKO ARUPEJAANI
ETSUTOORE PEROONE
PIEERUJOZETSUPE ORETSUTSUI
JUZETSUPE KATSUSHINETSURI
JOBANNI FURANCHESUKI
Application Number:
JP9276889A
Publication Date:
December 24, 1998
Filing Date:
April 12, 1989
Export Citation:
Assignee:
FUARUMASHIA E ATSUPUJON SPA
International Classes:
A61K31/43; A61K31/545; A61K31/546; A61P31/04; C07D499/00; C07D499/08; C07D499/28; C07D499/44; C07D499/86; C07D499/861; C07D499/87; C07D499/865; C07D499/897; C07D501/00; C07D501/02; C07D501/04; C07D501/20; (IPC1-7): C07D501/00; A61K31/43; A61K31/545; C07D499/28; C07D499/44; C07D499/86; C07D499/87; C07D499/897; C07D501/04; C07D501/20
Domestic Patent References:
| JP63198688A |
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)