Title:
【発明の名称】C-4カーボネートタキサン
Document Type and Number:
Japanese Patent JP2003523971
Kind Code:
A
Abstract:
The present invention concerns novel taxane derivatives, their use as antitumor agents, and pharmaceutical formulations.The invention claims compounds of formula I and the use of compounds of formula I or pharmaceutical salts thereof as oral drugs for the treatment of human or veterinary disease.in which:R is phenyl, isopropyl, or tert butyl;R<1 >is -C(O)Rin which Ris (CH3)3CO-, (CH3)3CCH2-, CH3(CH2)3O-, cyclobutyl-, cyclohexyloxy, or (2-furyl);R<2 >is CH3C(O)O-.
Inventors:
Kadou, John F
Masters, Harold
Shu, Kiufen May
Hansel, Stephen
Marie Edson, Zokler
Marie Edson, Zokler
Rose, william sea
Talent, James G
Masters, Harold
Shu, Kiufen May
Hansel, Stephen
Marie Edson, Zokler
Marie Edson, Zokler
Rose, william sea
Talent, James G
Application Number:
JP2001556256A
Publication Date:
August 12, 2003
Filing Date:
November 16, 2000
Export Citation:
Assignee:
Bristol-Myers Squibb Company
International Classes:
A61K31/335; A61K31/337; A61K31/341; A61P35/00; C07D305/14; C07D407/12; (IPC1-7): C07D305/14; A61K31/337; A61K31/341; A61P35/00; C07D407/12
Attorney, Agent or Firm:
Takehiko Saito (1 outside)