Title:
【発明の名称】炭素環式ヌクレオシドとその製造方法
Document Type and Number:
Japanese Patent JP2003508533
Kind Code:
A
Abstract:
The present invention provides a six membered, at least partially unsaturated, carbocyclic nucleoside compound, including the (-) enantiomer, the (+) enantiomer, and pharmaceutically acceptable salts and esters thereof. The compounds are represented by formula (I), wherein Z represents one double bond in the six membered carbocylic ring, B is a heterocyclic ring, such as a pyrimidine or purine base, X is an azido, F or OR2, R1 and R2 are the same or different and represent the same or different protecting groups, hydrogen, alkyl, alkenyl, acyl or phosphate moieties, and wherein the alkyl moiety is a saturated, optionally unsubstituted hydrocarbon having from 1 to 20 carbon atoms, the alkenyl moiety is an unsaturated congener of the alkyl group, and the acyl moiety is analkanoyl or aroyl moiety.
Inventors:
Pete Heldewain
Jin Wan
Eric de Clerc
Jin Wan
Eric de Clerc
Application Number:
JP2001522226A
Publication Date:
March 04, 2003
Filing Date:
September 08, 2000
Export Citation:
Assignee:
Stigching Regga We Z Way
International Classes:
A61K31/047; A61K31/216; A61K31/52; A61K31/522; A61K31/695; A61P31/12; A61P31/20; A61P31/22; C07C35/18; C07C69/013; C07D239/46; C07D473/00; C07D473/18; C07D473/34; C07D473/40; C07F7/18; C07F15/02; (IPC1-7): C07F7/18; A61K31/047; A61K31/216; A61K31/52; A61K31/522; A61K31/695; A61P31/12; A61P31/20; A61P31/22; C07D473/18; C07D473/34; C07D473/40
Foreign References:
| WO1999031055A1 | 1999-06-24 |
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)