Title:
【発明の名称】カルボン酸類及びその誘導体並びにそれらを含有する医薬組成物
Document Type and Number:
Japanese Patent JP2002507209
Kind Code:
A
Abstract:
In accordance with the present invention, there are provided therapeutically effective compounds comprising an amphipathic carboxylate of the formula R-COOH, or a salt or an ester or amide of such compound, where R designates a saturated or unsaturated alkyl chain of 10-24 carbon atoms, one or more of which may be replaced by heteroatoms, where one or more of said carbon or heteroatom chain members optionally forms part of a ring, and where said chain is optionally substituted by a hydrocarbyl radical, heterocyclyl radical, lower alkoxy, hydroxyl-substituted lower alkyl, hydroxyl, carboxyl, halogen, phenyl or (hydroxy-, lower alkyl-, lower alkoxy-, lower alkenyl- or lower alkinyl)-substituted phenyl, C3-C7 cycloalkyl or (hydroxy-, lower alkyl-, lower alkoxy-, lower alkenyl- or lower alkinyl)-substituted C3-C7 cycloalkyl wherein said amphipathic carboxylate is capable of being endogenously converted to its respective coenzyme A thioester.
More Like This:
Inventors:
Bartana, Jacob
Application Number:
JP50539899A
Publication Date:
March 05, 2002
Filing Date:
June 23, 1998
Export Citation:
Assignee:
Ism Research Development Company of the Hebrew University of Jerusalem
International Classes:
A61K31/00; A61K31/16; A61K31/19; A61K31/192; A61K31/20; A61K31/201; A61K31/202; A61K31/23; A61K31/231; A61K31/232; A61K31/69; A61P3/10; A61P7/02; A61P9/10; A61P9/12; A61P17/06; A61P19/02; A61P25/00; A61P3/06; A61P29/00; A61P35/00; A61P43/00; (IPC1-7): A61K31/20; A61K31/16; A61K31/201; A61K31/202; A61K31/23; A61K31/231; A61K31/232; A61P3/06; A61P3/10; A61P7/02; A61P9/10; A61P9/12; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P43/00
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)