Title:
【発明の名称】コラーゲンペプチドフラクション及びその使用
Document Type and Number:
Japanese Patent JPH11507918
Kind Code:
A
Abstract:
It was found that a collagen peptide fraction (CPF) of especially porcine collagen >70 %, especially >80 %, of which have an average molecular weight of 8-30 kDa, a hydroxyproline content of 15-19 %, a proline content of 18-22 % and a glycine content of 27-33 % which is stable at temperatures up to 150 DEG C, and shows a viscosity of 2.0 to 3.0 cSt [mm<2>/sec] at a concentration of 10 % in water and an UV absorbance at 280 nm of 0.6 to 1.8 has a surprising stabilising effect on protein and polypeptides in freeze dried form and in solution. CPF-stabilised proteins and polypeptide drugs can be used during long term infusion or for topical, nasal or transdermal application.
Inventors:
Stocker Kurz
Gaffney Patrick J.
Gaffney Patrick J.
Application Number:
JP50259296A
Publication Date:
July 13, 1999
Filing Date:
June 06, 1996
Export Citation:
Assignee:
Pentafarm AG
International Classes:
A61K47/42; B01J20/281; C07K1/02; C07K14/78; G01N30/26; G01N30/88; G01N33/531; G01N33/543; (IPC1-7): C07K14/78; A61K47/42; C07K1/02; G01N30/26; G01N30/48; G01N33/531
Attorney, Agent or Firm:
Kenji Saeki