Title:
【発明の名称】B.MICROTI感染の診断および処置のための、化合物および方法
Document Type and Number:
Japanese Patent JP2003517282
Kind Code:
A
Abstract:
Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen, DNA sequences encoding such polypeptides, and fusion proteins comprising such polypeptides. Antigenic epitopes of such antigens are also provided, together with pharmaceutical compositions and vaccines comprising such polypeptides, DNA sequences, fusion proteins or antigenic epitopes. Diagnostic kits containing such polypeptides, DNA sequences, fusion proteins or antigenic epitopes and a suitable detection reagent may be used for the detection of B. microti infection in patients and biological samples. Antibodies directed against such polypeptides and antigenic epitopes are also provided.
Inventors:
Reed, Stephen G.
Rodes, Michael Jay.
Houghton, Raymond Elle.
Threes, Paul Earl.
McNail, Patricia Dee.
Rodes, Michael Jay.
Houghton, Raymond Elle.
Threes, Paul Earl.
McNail, Patricia Dee.
Application Number:
JP2000609581A
Publication Date:
May 27, 2003
Filing Date:
April 05, 2000
Export Citation:
Assignee:
Corixa Corporation
International Classes:
G01N33/564; A61K39/018; C07K14/44; C07K16/20; C07K17/08; C07K19/00; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/30; C12P21/08; C12Q1/68; G01N33/566; G01N33/569; G01N33/577; A61K38/00; A61K39/00; C12R1/90; (IPC1-7): C12N15/09; A61K39/018; C07K14/44; C07K16/20; C07K17/08; C07K19/00; C12N1/19; C12N1/21; C12N5/10; C12Q1/68; G01N33/564; G01N33/566; G01N33/569; G01N33/577
Attorney, Agent or Firm:
Shusaku Yamamoto