Title:
【発明の名称】環状エーテルビタミンD3化合物、1α(OH)3-エピ-ビタミンD3化合物及びそれらの使用法
Document Type and Number:
Japanese Patent JP2002505668
Kind Code:
A
Abstract:
Novel cyclic ether vitamin D3 compounds having a cyclic ether side chain are disclosed. These compounds were first identified as metabolites of 3-epi vitamin D3 produced via a tissue-specific metabolic pathway which catalyzes the formation of a cyclic ether structure. Also disclosed are 1alpha(OH) 3-epi vitamin D3 compounds, which are produced via the epimerization of a 3-beta-hydroxyl group of 1alpha(OH) vitamin D3 precursor in vivo. The vitamin D3 compounds of the present invention can be used as substitutes for natural and synthetic vitamin D3 compounds.
Inventors:
Lady Sataya Narayana Gee.
Application Number:
JP54963098A
Publication Date:
February 19, 2002
Filing Date:
May 15, 1998
Export Citation:
Assignee:
Women and Infants Hospital
International Classes:
A61K31/045; A61K31/351; A61P3/00; A61P3/02; A61P3/14; A61P5/18; A61P17/00; A61P19/08; A61P19/10; A61P43/00; C07C401/00; C07D303/14; C07D307/33; C07D309/04; C07D309/06; (IPC1-7): C07C401/00; A61K31/045; A61K31/351; A61P3/00; A61P3/02; A61P3/14; A61P5/18; A61P17/00; A61P19/08; A61P19/10; A61P43/00; C07D309/04; C07D309/06
Attorney, Agent or Firm:
Yoshiki Ishida (1 person outside)