Title:
【発明の名称】減感作剤
Document Type and Number:
Japanese Patent JP2594123
Kind Code:
B2
Abstract:
A novel hyposensitization agent was prepared by covalently attaching a saccharide, e.g. homo- and heteroglycans, for example, starch, amylose, dextran, polysucrose, pullulan, elsinan, curdlan, gum arabic, gum tragacanth, guar gum, xanthan gum, carrageenan, pectin, cellulose, glucomannan, chitosan, and lipopolysaccharide, and their derivatives and partial hydrolysates to, a cedar pollen allergen. The hyposensitization agent can be administered to a cedar pollinosis patient without fear of eliciting anaphylaxis and allergy within a shortened hyposensitization period because the hyposensitization agent much more enhances the producibilities of immunoglobulin G and M antibodies which are specific to intact cedar pollen allergen, but extremely reduces the producibility of immunoglobulin E antibody which is specific to the allergen and responsible for anaphylaxis and allergy.
Inventors:
Nao Matsuhashi
Usui Mitsuko
Masakazu Mitsuhashi
Shun Ando
Usui Mitsuko
Masakazu Mitsuhashi
Shun Ando
Application Number:
JP18448788A
Publication Date:
March 26, 1997
Filing Date:
July 26, 1988
Export Citation:
Assignee:
Hayashibara Institute of Biochemistry
International Classes:
A61K39/36; A61K47/48; A61P37/08; (IPC1-7): A61K39/36