Title:
【発明の名称】ジアシルヒドラジン誘導体
Document Type and Number:
Japanese Patent JP2003505365
Kind Code:
A
Abstract:
Diacylhydrazine derivatives of general formula (I)wherein X, Y, Z, R<1>, <2 >and R<3 >are as defined herein, and their physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be used to combat thromboses, myocardial infarcts, coronary cardiac diseases, arteriosclerosis, inflammations, tumors, osteoporosis, infections, and restenosis following angioplasty or during pathological processes that are maintained or propagated by angiogenesis.
Inventors:
Holtzmann, Gunter
Goodman, Gimon
Kessler, Horst
Gibson, Christoph
Zurik, Gabor
Goodman, Gimon
Kessler, Horst
Gibson, Christoph
Zurik, Gabor
Application Number:
JP2001511414A
Publication Date:
February 12, 2003
Filing Date:
July 05, 2000
Export Citation:
Assignee:
Merck Patent Gesellschaft Mitt Beschlenktel Haftung
International Classes:
A61K31/194; A61K31/197; A61K31/198; A61K31/4168; A61K31/4402; A61K31/4409; A61P7/02; A61P9/00; A61P9/02; A61P9/08; A61P9/10; A61P19/00; A61P19/10; A61P29/00; A61P31/00; A61P35/00; C07D233/88; C07C243/24; C07C257/14; C07C277/08; C07C279/14; C07C279/18; C07C281/02; C07C281/06; C07D213/74; (IPC1-7): C07C279/18; A61K31/194; A61K31/198; A61K31/4168; A61K31/4409; A61P7/02; A61P9/08; A61P9/10; A61P19/10; A61P29/00; A61P35/00; C07C277/08; C07C281/06; C07D213/74; C07D233/88
Attorney, Agent or Firm:
Kiyokazu
Previous Patent: 特定の特性を有するアミノグアニジンビカーボネートおよびそれの製造方...
Next Patent: ２−メトキシ−４−（Ｎ−ｔ−ブチルアミノカルボニル）ベンゼンスルホ...
Next Patent: ２−メトキシ−４−（Ｎ−ｔ−ブチルアミノカルボニル）ベンゼンスルホ...