Title:
【発明の名称】インスリン依存性糖尿病の診断と治療
Document Type and Number:
Japanese Patent JP3165148
Kind Code:
B2
Abstract:
A 65 KD heat shock protein, proteins cross-reactive therewith, or antibodies thereto can be used for detecting in humans the existence of, a tendency to develop, or the initiation of a process leading to insulin dependent diabetes mellitus. Antibodies to hsp65 can be used to detect the hsp65 molecule in blood or urine. The hsp65 molecule of any species, or any other substance immunologically cross-reactive therewith, when administered with a tolerogenic carrier, can be used for the prevention or treatment of IDDM prior to development of clinical symptoms thereof.
Inventors:
Cohen, Irun, Earl
Elias, Dana
Markovitz, Delon
Elias, Dana
Markovitz, Delon
Application Number:
JP50811690A
Publication Date:
May 14, 2001
Filing Date:
March 14, 1990
Export Citation:
Assignee:
Yeda Research and Development Company Limited
International Classes:
A61K35/12; A61K35/14; A61K35/26; C12N15/09; A61K38/00; A61K38/16; A61K39/00; A61K39/395; A61K49/00; A61P3/08; A61P3/10; C07K14/35; C07K14/435; C07K14/47; C07K14/52; C07K14/725; C07K16/00; C07K16/12; C07K16/18; C07K19/00; C12N1/21; G01N33/49; G01N33/53; G01N33/564; G01N33/68; (IPC1-7): C07K14/47; A61K38/00; A61P3/10
Other References:
Ｍｏｌ．Ｃｅｌｌ．Ｂｉｏｌ．Ｖｏｌ．９，Ｎｏ．５（１９８９．Ｍａｙ）ｐ．２２７９−２２８３
Attorney, Agent or Firm:
Akira Asamura (3 outside)