Title:
【発明の名称】増強循環エフェクター組成物および方法
Document Type and Number:
Japanese Patent JPH08508256
Kind Code:
A
Abstract:
A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal ends of the polymer chains. In one embodiment, the effector is polymyxin B, for treatment of septic shock.
Inventors:
Zalipsky, Samuel
Woodle, Martin Sea.
Martin, Francis Jay.
Barrenholtz, Eticl
Woodle, Martin Sea.
Martin, Francis Jay.
Barrenholtz, Eticl
Application Number:
JP52133294A
Publication Date:
September 03, 1996
Filing Date:
March 22, 1994
Export Citation:
Assignee:
Sicius Pharmaceuticals, Incorporated
International Classes:
A61K9/127; A61K31/715; A61K38/00; A61K38/21; A61K38/22; A61K39/395; A61K47/48; A61P5/18; A61P7/00; A61P9/00; A61P29/00; A61P31/04; A61P31/12; A61P31/18; A61P35/00; A61P35/04; A61P37/06; A61P43/00; (IPC1-7): A61K9/127; A61K38/00; A61K38/22; A61K39/395
Attorney, Agent or Firm:
Shusaku Yamamoto