Title:
【発明の名称】小細胞肺癌に対するフコーシルGM-1-KLH接合体ワクチン
Document Type and Number:
Japanese Patent JP2001517638
Kind Code:
A
Abstract:
This invention provides for a composition comprising a fucosyl GM1 ganglioside or an oligosaccharide thereof conjugated to an immunogenic protein, an adjuvant, the amounts thereof being effective to stimulate or enhance antibody production in a subject, and a pharmaceutically acceptable carrier. This invention also provides a method of stimulating antibody production in a subject which comprises administering to the subject an effective amount of the above-described composition to stimulate antibody production. This invention also provides a method of enhancing antibody production in a subject which comprises administering to the subject an effective amount of the above-described composition to enhance antibody production. This invention also provides a method of preventing cancer in a subject which comprises administering to the subject an amount of the above-described composition effective to prevent cancer. This invention also provides a method of treating cancer in a subject which comprises administering to the subject an amount of the above-described composition effective to treat cancer.
Inventors:
Livingston, Philip O
Rug patch, Gobinda Swami
Rug patch, Gobinda Swami
Application Number:
JP2000512569A
Publication Date:
October 09, 2001
Filing Date:
September 25, 1998
Export Citation:
Assignee:
Sloan-Kettering Institute for Cancer Research
International Classes:
A61K47/42; A61K39/00; A61K39/385; A61K39/39; A61K47/48; A61P35/00; (IPC1-7): A61K39/385; A61K39/39; A61K47/42; A61P35/00
Attorney, Agent or Firm:
Takehiko Suzue (4 outside)