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Title:
【発明の名称】融合タンパク質および粒子
Document Type and Number:
Japanese Patent JP2708046
Kind Code:
B2
Abstract:
Fusion proteins comprise a first amino acid sequence and a second amino acid sequence. The first amino acid sequence is derived from a retrotransposon or an RNA retrovirus and confers on the fusion protein the ability to assemble into particles; an example is the product of the TYA gene of the yeast retrotransposon Ty. The second amino acid sequence is biologically active; for example it may be antigenic. So particles formed of the fusion proteins may be useful in vaccines or in diagnostic or purification applications.

Inventors:
Kingsman, Alan, John
Kingsman, Susan, Mary
Adams, Sally, Elizabeth
Marim, michael henry
Mellow, Elizabeth-Jane Crier
Application Number:
JP50666487A
Publication Date:
February 04, 1998
Filing Date:
October 28, 1987
Export Citation:
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Assignee:
British Biotech Pharmaceuticals Limited
International Classes:
A61K39/21; A61K39/395; A61P31/12; C07H21/04; G01N33/569; C07K14/00; C07K14/11; C07K14/16; C07K14/195; C07K14/41; C07K14/44; C07K14/52; C07K14/555; C07K16/00; C07K19/00; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/62; C12P21/00; C12P21/02; C12P21/08; C12R1/19; C12R1/865; (IPC1-7): C12P21/02; C07K19/00; C12N15/09; G01N33/569
Domestic Patent References:
JPS6067859A
JPS6193199A
Other References:
Nature,313(1985)P.243−246
Attorney, Agent or Firm:
Shintaro Nogawa