Title:
【発明の名称】テナガザル白血球ウイルスベースのレトロウイルスベクター
Document Type and Number:
Japanese Patent JPH08511156
Kind Code:
A
Abstract:
PCT No. PCT/US94/03784 Sec. 371 Date Feb. 24, 1997 Sec. 102(e) Date Feb. 24, 1997 PCT Filed Apr. 6, 1994 PCT Pub. No. WO94/23048 PCT Pub. Date Oct. 13, 1994The present invention provides replication-defective hybrid retroviral vectors comprising GaLV components and methods for preparing and using such vectors. The vectors comprise a envelope component, a core component and a defective genome, at least one of which is derived from GaLV. The vectors can comprise the minimal cis acting sequences from GaLV that allow packaging of the defective genome in a hybrid virion.
Inventors:
Aiden, Marie Beth Buoy.
Wilson, Caroline A.
Deacon, Nicholas Jay.
Hooker, David Jay.
Wilson, Caroline A.
Deacon, Nicholas Jay.
Hooker, David Jay.
Application Number:
JP52248694A
Publication Date:
November 26, 1996
Filing Date:
April 06, 1994
Export Citation:
Assignee:
US GOV HEALTH & HUMAN SERV (US)
International Classes:
C12N15/09; A61K31/70; A61K35/76; A61K48/00; C07H21/04; C07K14/15; C12N5/10; C12N7/00; C12N7/01; C12N15/48; C12N15/867; (IPC1-7): C12N15/09; A61K31/70; A61K48/00; C07H21/04; C12N5/10; C12N7/00
Attorney, Agent or Firm:
Takashi Ishida (3 others)