Title:
【発明の名称】H+-ATPaseとしての複素環式化合物
Document Type and Number:
Japanese Patent JPH11514361
Kind Code:
A
Abstract:
PCT No. PCT/JP96/02981 Sec. 371 Date Apr. 14, 1998 Sec. 102(e) Date Apr. 14, 1998 PCT Filed Oct. 15, 1996 PCT Pub. No. WO97/14681 PCT Pub. Date Apr. 24, 1996This invention relates to a quinoline compound of the formula: wherein R1 is a pyridyl group or aryl, each of which may be substituted with suitable substituent(s), A is -COHN- or -NHCO-, n is an integer of 0 or 1, and is a group of the formula: In which R2, R3, R4, R5, R6 and R7 are as defined, and pharmaceutically acceptable salt thereof, to processes for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prevention and/or the treatment of bone diseases caused by abnormal bone metabolism in human being or animals.
Inventors:
Teruo Oku
Yoshio Kawai
Shigeki Sato
Hitoshi Yamazaki
Kayari Natsuko
Taiji Urano
Yoshihara Kosei
Noriko Yoshida
Yoshio Kawai
Shigeki Sato
Hitoshi Yamazaki
Kayari Natsuko
Taiji Urano
Yoshihara Kosei
Noriko Yoshida
Application Number:
JP51568097A
Publication Date:
December 07, 1999
Filing Date:
October 15, 1996
Export Citation:
Assignee:
Fujisawa Pharmaceutical Co., Ltd.
International Classes:
A61K31/00; A61K31/435; A61K31/4353; A61K31/4365; A61K31/47; A61K31/4706; A61K31/472; A61K31/4725; A61K31/4738; A61K31/4745; A61K31/495; A61K31/496; A61K31/505; A61K31/513; A61K31/517; A61K31/529; A61K31/535; A61K31/5375; A61K31/5377; A61K31/54; A61K31/542; A61P19/00; A61P19/08; C07D215/20; C07D215/40; C07D215/42; C07D215/44; C07D215/46; C07D215/48; C07D215/54; C07D215/56; C07D215/60; C07D221/12; C07D237/28; C07D239/74; C07D239/88; C07D239/94; C07D241/42; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D471/04; C07D495/04; C07D513/04; C07D513/14; C07D521/00; C07F7/08; C07F7/10; C07F7/18; (IPC1-7): C07D215/20; C07F7/18; C07F7/10; C07D513/04; C07D495/04; C07D471/04; C07D417/12; C07D413/12; C07D409/12; C07D405/12; C07D403/04; C07D401/14; C07D401/12; C07D401/06; C07D401/04; C07D239/94; C07D237/28; C07D215/40; A61K31/54; A61K31/535; A61K31/505; A61K31/495; A61K31/47; A61K31/435; A61K31/00