Title:
【発明の名称】マイコバクテリウム・ワッカエ由来のホルモンおよび成長因子ホスホグリカン模倣物
Document Type and Number:
Japanese Patent JPH11503307
Kind Code:
A
Abstract:
PCT No. PCT/GB96/00669 Sec. 371 Date Feb. 2, 1998 Sec. 102(e) Date Feb. 2, 1998 PCT Filed Mar. 20, 1996 PCT Pub. No. WO96/29425 PCT Pub. Date Sep. 26, 1996A hormone or growth factor mimetic second messenger is derived from a microorganism of the genus Mycobacterium, suitably M. vaccae. The mimetic second messenger may mimic the action of insulin, ACTH, NGF, EGF, FGF, TGF beta or HGF. Further, methods of treating type I or type II diabetes mellitus, polycystic ovary syndrome, central nervous system damage, hepatic damage, alcohol abuse, drug sensitivity, tissue damage, adrenal atrophy, etc., are also disclosed. The methods are carried out by administering the mimetic second messenger to a patient in need thereof.
Inventors:
Rade Marker Thomas William
Caro Hugo Norbert
Luke Graham Arthur William
Caro Hugo Norbert
Luke Graham Arthur William
Application Number:
JP52819996A
Publication Date:
March 26, 1999
Filing Date:
March 20, 1996
Export Citation:
Assignee:
University College London
International Classes:
A61K38/00; A61K39/04; A61P3/00; A61P3/06; C12P19/00; A61P3/08; A61P9/00; A61P13/02; A61P15/00; A61P25/00; A61P31/00; A61P37/00; A61P43/00; C07H11/04; C07K14/35; C12P19/46; C12R1/32; (IPC1-7): C12P19/00; A61K38/00
Attorney, Agent or Firm:
Eiji Saegusa (10 others)