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Title:
【発明の名称】ヒト脱共役タンパク質3
Document Type and Number:
Japanese Patent JP2002502240
Kind Code:
A
Abstract:
An isolated nucleic acid molecule is disclosed which encodes a novel human uncoupling protein (UCP3), and related recombinant expression vectors, recombinant host cells and substantially purified forms of the UCP3 protein. The isolated nucleic acid and proteins disclosed herein will be useful in methods associated with identifying compounds which modulate energy expenditure and body weight regulation, as well as effecting diseases such as obesity and diabetes as well as mitochondria-associated hypermetabolism. Additionally, the isolated nucleic acids of the present invention are candidates for gene therapy of a mammalian host, including humans.

Inventors:
Liu, Ching Yun
Chiang, Juan
Application Number:
JP55052298A
Publication Date:
January 22, 2002
Filing Date:
May 19, 1998
Export Citation:
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Assignee:
Merck End Company, Inc.
International Classes:
C12N15/09; A61K31/7088; A61K38/00; A61K48/00; A61P3/04; A61P3/10; A61P43/00; C07K14/47; C07K14/575; C12N1/19; C12N5/10; C12P21/06; C12Q1/68; (IPC1-7): C12N15/09; A61K31/7088; A61K38/00; A61K48/00; A61P3/04; A61P3/10; A61P43/00; C07K14/47; C12N1/19; C12N5/10; C12P21/06; C12Q1/68
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)