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Title:
【発明の名称】ヒドラゾンの塩
Document Type and Number:
Japanese Patent JP2788579
Kind Code:
B2
Abstract:
The invention relates to acid addition salts of bases of the formula I in which A, R1, R2, R3, R4, R5, X and Z have the meanings given in the description, with an acid [PA], which denotes a mono- or polybasic acid selected from carbonic acid, alkanoic acids which are unsubstituted or monosubstituted to polysubstituted, apart from formic acid, unsubstituted acetic acid, lysine and arginine; alkenoic acids which are unsubstituted or substituted, apart from unsubstituted fumaric acid, cycloalkylcarboxylic acids, arylcarboxylic acids, aryl-lower alkylcarboxylic acids in which lower alkyl is unsubstituted or substituted, aryl-lower alkenylcarboxylic acids, heterocyclylcarboxylic acids, alkanesulphonic acids which are unsubstituted or substituted, apart from unsubstituted methanesulphonic acid, aromatic sulphonic acids, alkylsulphuric acids, N-substituted sulphamic acids, organic acids without carboxyl, sulpho, sulphate or phospho groups, and further from pyrophosphoric acid and hydrogen iodide; and tautomers thereof. The acid addition salts are employed for the treatment of disorders which respond to inhibition of S-adenosylmethionine decarboxylase.

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Inventors:
YAROSURAFU SHUTANEKU
IERUKU FURAI
JORUJIO KARABATSUTEI
Application Number:
JP26835392A
Publication Date:
August 20, 1998
Filing Date:
October 07, 1992
Export Citation:
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Assignee:
NOBARUTEISU AG
International Classes:
A61K31/15; A61K31/155; A61K31/17; A61K31/18; A61K31/185; A61K31/19; A61P31/00; A61P33/02; A61P33/06; A61P35/00; A61P35/04; A61K31/165; C07C51/41; C07C251/80; C07C281/18; C07C303/32; C07C309/05; C07C309/29; C07C309/35; C07C327/48; C07C337/08; (IPC1-7): C07C281/18; A61K31/165; A61K31/17; A61K31/185; A61K31/19; C07C303/32; C07C309/05; C07C309/29; C07C309/35; C07C327/48; C07C337/08
Attorney, Agent or Firm:
Aoki Akira (3 outside)



 
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