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Title:
IMIDAZOQUINOLINE DERIVATIVE
Document Type and Number:
Japanese Patent JPH07112983
Kind Code:
A
Abstract:

PURPOSE: To provide a novel compound having a platelet coagulation-inhibiting action, an anti-arteriosclerosis action and an anti-anginal action.

CONSTITUTION: A compound of formula I (when one of A, B is N, the other is C; R1, R2 are formyl, a dialkylamino; R3, R4 are H, a halogen; dotted line expresses the presence of an aromatic double bond), e.g. 4-chloro-3-formyl-1- dimethylaminoimida [1, 5-a] quinoline. The compound of formula I is obtained by reacting a 2-cyanoquinoline of formula II with Vilsmeier reagent prepared from an N,N-dialkylformaldehyde and a phosphorus oxyhalide. The compound of formula I is useful as an agent for treating circulatory diseases, and is administered at daily a dose of approximately 200-3000 mg once to several times a day for an adult.


Inventors:
HIROTA TAKASHI
Application Number:
JP28065293A
Publication Date:
May 02, 1995
Filing Date:
October 15, 1993
Export Citation:
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Assignee:
LEDERLE JAPAN LTD
International Classes:
C07D471/04; A61K31/47; A61P7/02; A61P9/00; A61P9/10; (IPC1-7): C07D471/04; A61K31/47



 
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