Title:
【発明の名称】インテグリンアンタゴニスト
Document Type and Number:
Japanese Patent JP2001509176
Kind Code:
A
Abstract:
This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. The vitronectin receptor antagonist compounds of the present invention are alpha v beta 3 antagonists, alpha v beta 5 antagonists or dual alpha v beta 3/ alpha v beta 5 antagonists useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, viral disease, and tumor growth.
Inventors:
Deyugan, Mark Yee
Application Number:
JP53447398A
Publication Date:
July 10, 2001
Filing Date:
January 13, 1998
Export Citation:
Assignee:
Merck End Company, Inc.
International Classes:
C07D235/16; A61K31/198; A61K31/4184; A61K31/4375; A61K31/44; A61K31/66; A61K45/06; A61P9/10; A61P19/10; A61P27/02; A61P29/00; A61P31/12; A61P35/00; A61P43/00; C07D213/73; C07D471/04; (IPC1-7): C07D213/73; A61K31/198; A61K45/06; A61P9/10; A61P27/02; A61P29/00; A61P31/12; A61P35/00; C07D235/16; C07D471/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)