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Title:
【発明の名称】侵入性微生物
Document Type and Number:
Japanese Patent JP2693948
Kind Code:
B2
Abstract:
Novel methods and microorganisms are provided, where novel genetic mammalian cell invasive capability is imparted to a microorganism by the introduction of an exogenous inv gene. The resulting organisms are then capable of binding to mammalian cells and are transferred to the cytoplasm. Other novel genetic capabilities may be imparted to the unicellular microorganism, so that the unicellular microorganism may serve as a vaccine for one or more pathogens or may introduce genetic capabilities or foreign molecules into a mammalian host cell.

Inventors:
Ralph Earl. Isberg
Stanley Huarco
Application Number:
JP17897486A
Publication Date:
December 24, 1997
Filing Date:
July 31, 1986
Export Citation:
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Assignee:
The Board of Trustees of the Reland Stanford-The Giunia University
International Classes:
A61K35/12; A61K35/74; A61K35/76; A61K38/00; A61K39/00; A61K39/108; C07K14/24; C07K14/255; C12N1/21; C12N15/00; C12N15/09; C12N1/20; C12N15/31; C12N15/85; C12N15/87; C12P21/00; C12P21/02; C12R1/19; (IPC1-7): C12N1/21; A61K35/74; A61K39/00; A61K39/108; C12P21/02
Attorney, Agent or Firm:
Aoki Akira (4 outside)