Title:
【発明の名称】血管内皮成長因子受容体のためのリガンド
Document Type and Number:
Japanese Patent JP2003528824
Kind Code:
A
Abstract:
The present invention relates to compositions comprised of a peptide ligand or derivatives thereof that are capable of specific binding to the high affinity receptor-1 of vascular endothelial growth factor (VEGF) and structure similar receptors. The invention further provides a peptide ligand or derivatives thereof that are capable of inhibiting angiogenesis induced by VEGF. The present invention also provides a method for treatment or diagnosis of disease associated with angiogenesis in a patient in need of therapy comprising administering to the patient an effective amount of the pharmaceutical composition of the present invention and a pharmaceutical acceptable carrier.
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Inventors:
Chischacova, Rio Udomira
Li, Shen Min
Pietrzinsky, Gruzegorz
Arachob, Valerie
Li, Shen Min
Pietrzinsky, Gruzegorz
Arachob, Valerie
Application Number:
JP2001557898A
Publication Date:
September 30, 2003
Filing Date:
February 02, 2001
Export Citation:
Assignee:
Splatec Pharmaceuticals Incorporated
International Classes:
C12N15/09; A61K38/00; A61P7/02; A61P9/00; A61P9/10; A61P9/14; A61P11/00; A61P17/02; A61P17/06; A61P29/00; A61P35/00; A61P35/04; A61P43/00; C07K7/08; C07K14/52; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C40B40/02; C40B50/06; A61K48/00; (IPC1-7): A61K38/00; A61P7/02; A61P9/00; A61P9/10; A61P9/14; A61P11/00; A61P17/02; A61P17/06; A61P29/00; A61P35/00; A61P35/04; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09
Attorney, Agent or Firm:
Takashi Ishida (4 others)