Title:
【発明の名称】芳香族代謝/Iからの物質の微生物による製造
Document Type and Number:
Japanese Patent JP2001506486
Kind Code:
A
Abstract:
The invention makes available, by means of an increased provision of intracellular metabolic intermediates, in particular of erythrose 4-phosphate, alternative processes for the microbial preparation of substances, in particular of aromatic amino acids such as L-phenylalanine, in which processes the activity of a transaldolase is increased in a microorganism producing these substances. In preferred embodiments of the invention, the activity of a transketolase or the activity of a transport protein for the PEP-independent uptake of a sugar and/or the activity of a kinase which phosporylates the relevant sugar are/is additionally increased. The invention also relates to gene structures, and to transformed cells carrying these gene structures, which make it possible to implement these processes in a particularly successful manner.
Inventors:
Splenger, Georg
Seeve, Ruth
Herman
Cult, martin
Songe, Theodorus
Seeve, Ruth
Herman
Cult, martin
Songe, Theodorus
Application Number:
JP52031898A
Publication Date:
May 22, 2001
Filing Date:
October 17, 1997
Export Citation:
Assignee:
Holland Sweetener Company V.O.F.
Forsung Zentrum Jürich Gamebha
Forsung Zentrum Jürich Gamebha
International Classes:
C12N15/09; C07H11/04; C07K14/195; C12N1/21; C12N9/10; C12N9/12; C12N15/31; C12N15/54; C12N15/63; C12P1/00; C12P13/22; C12P19/02; C12R1/07; C12R1/13; C12R1/15; C12R1/185; C12R1/425; (IPC1-7): C12P13/22; C12N1/21; C12N15/09
Attorney, Agent or Firm:
Mitsuo Matsui