Title:
【発明の名称】金属キレート化合物
Document Type and Number:
Japanese Patent JP2860166
Kind Code:
B2
Abstract:
Ligands for radiopharmaceutical use are capable of chelating radiometal species and of being bound to biological targeting molecules. The ligands have the formula where A, A' = -SZ or Y B = O or S Y = Z = H or a thiol protecting group m = 2 or 3 n = 2 or 3 q = 0 or 1 R = H or unsubstituted or substituted hydrocarbon and pharmaceutically acceptable salts, provided that at least one CR2 group represents CO and forms, together with an adjacent N atom, a -CONR- amide group.
Inventors:
AACHAA KORIN MIRU
BOWAA GEIRII ROBAATO
JIRU HARUJITSUTO KAA
RIRII ANSONII REONAADO MAAKU
SUTOORII ANSONII IIMON
KANINGU RUISU RYUUBEN
GURIFUISU DEEBITSUDO UOOGAN
BOWAA GEIRII ROBAATO
JIRU HARUJITSUTO KAA
RIRII ANSONII REONAADO MAAKU
SUTOORII ANSONII IIMON
KANINGU RUISU RYUUBEN
GURIFUISU DEEBITSUDO UOOGAN
Application Number:
JP52184494A
Publication Date:
February 24, 1999
Filing Date:
March 31, 1994
Export Citation:
Assignee:
AMERUSHAMU INTERN PLC
International Classes:
C07D249/00; A61K47/48; A61K51/00; A61K51/04; C07B59/00; C07C323/40; C07C323/60; C07C327/00; C07D233/28; C07D233/91; C07D309/08; C07D401/06; C07D405/12; C07F5/00; C07F13/00; C07K5/06; C07K5/062; C07K5/083; (IPC1-7): C07C323/60; C07C323/40; C07D233/91; C07D309/08; C07D401/06; C07D405/12; C07F13/00; C07K5/062; C07K5/083
Domestic Patent References:
| JPH04505152A | 1992-09-10 | |||
| JPH05221958A | 1993-08-31 |
Foreign References:
| WO1991016076A1 | 1991-10-31 |
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)