Title:
【発明の名称】β-アミノ-α-ヒドロキシカルボン酸及びその誘導体の製造方法
Document Type and Number:
Japanese Patent JPH11508567
Kind Code:
A
Abstract:
PCT No. PCT/EP96/02573 Sec. 371 Date Jun. 1, 1998 Sec. 102(e) Date Jun. 1, 1998 PCT Filed Jun. 14, 1996 PCT Pub. No. WO97/02236 PCT Pub. Date Jan. 23, 1997Disclosed is a process for producing beta -amino- alpha -hydroxycarboxylic acid derivatives of general formula (2R,3S)- or (2S,3E)-N-(X,Y)-3-amino-2-hydroxy-3-phenyl propionic acid-Z of Formula I, e.g. of (2E,3S)-3-amino-2-hydroxy-3-phenyl propionic acid or (2R,3S)-N-benzoyl-3-amino-2-hydroxy-3-phenyl propionic acid methylester. Compounds of type I are valuable intermediates in the total synthesis of Taxols which can be used in the treatment of various forms of cancer.
Inventors:
Claus Stingle
Matthias Kottenhan
Karl Heinz Drouts
Matthias Kottenhan
Karl Heinz Drouts
Application Number:
JP50474897A
Publication Date:
July 27, 1999
Filing Date:
June 14, 1996
Export Citation:
Assignee:
Degussa Actien Gezel Shaft
International Classes:
C07C213/00; C07C227/26; C07C229/34; C07C231/12; C07C233/51; C07C269/06; C07D305/14; (IPC1-7): C07C229/34; C07C227/26; C07C231/12; C07C233/51
Attorney, Agent or Firm:
Toshio Yano (3 outside)