Title:
【発明の名称】N-アクリロイル-α-アミノ酸の提供方法
Document Type and Number:
Japanese Patent JPH0749403
Kind Code:
B2
Abstract:
A novel, one-pot procedure for the preparation of N-acryloyl- alpha -amino acids involves the steps of: i) reacting a ketone, an ammonium salt, and a cyanide salt in water, optionally in the presence of ammonium hydroxide and a co-solvent, to form an aminonitrile; ii) acryloylating the aminonitrile in aqueous media to afford an acrylamidonitrile; and iii) hydrolyzing with aqueous acid the acrylamidonitrile to provide the N-acryloyl- alpha -amino acid.
Inventors:
Larry Richard Kreppski
Howell Kurtz Smith, Junior
Gerald Kenneth Rasmussen
Stevens Mikle Haleman
Howell Kurtz Smith, Junior
Gerald Kenneth Rasmussen
Stevens Mikle Haleman
Application Number:
JP12100187A
Publication Date:
May 31, 1995
Filing Date:
May 18, 1987
Export Citation:
Assignee:
Minnesota Mining and Manyufu Actuating Company
International Classes:
C07C231/06; A61K6/00; C07B41/08; C07B43/06; C07C67/00; C07C231/00; C07C231/12; C07C231/14; C07C233/45; C07C233/49; (IPC1-7): C07C233/49; C07B41/08; C07B43/06; C07C231/14
Attorney, Agent or Firm:
Akira Asamura (2 outside)
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