Title:
【発明の名称】ナフトエ酸誘導体
Document Type and Number:
Japanese Patent JP2671059
Kind Code:
B2
Abstract:
A naphthoic acid derivative represented by the following general formula or a salt thereof: wherein R1, R2 and R3 are each independently a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, a lower alkanoyloxy group, a hydroxy-lower alkyl group, a lower alkoxy-lower alkyl group, a lower alkanoyloxy-lower alkyl group or an aralkyloxy group; R4 is a hydrogen atom or a lower alkyl group; R5 is a substituted or unsubstituted aryl group or a substituted or unsubstituted heteroaromatic group; X is a group a cycloalkylene group, a bivalent nitrogen-containing heterocyclic group, or a group -R8- NH- or -NH-R8, where R6 and R7 are each a hydrogen atom or a lower alkyl group and R8 is a cycloalkylene group, or R6 and R7, together with R4, may form an alkylene group of 1-3 carbon atoms; Y is -S(O)p-, -(CH2)n- or -O-; Z is a substituted or unsubstituted alkylene group or a single bond; l is an integer of 0-4; m is an integer of 0-8; n is 0 or 1; p is an integer of 0-2; and g is 0 or 1. The compound is useful as an antiallergic agent.
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Inventors:
Yasuo Sekine
Masato Nishimura
Yasuko Emoto
Tetsuaki Yamaura
Eri Kojima
Yasushi Higashide
Masato Nishimura
Yasuko Emoto
Tetsuaki Yamaura
Eri Kojima
Yasushi Higashide
Application Number:
JP33000490A
Publication Date:
October 29, 1997
Filing Date:
November 30, 1990
Export Citation:
Assignee:
FUJIREBIO INC.
International Classes:
A61K31/215; A61K31/34; A61K31/341; A61K31/38; A61K31/381; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/4427; A61K31/4433; A61K31/445; A61K31/495; A61P37/08; A61P43/00; C07C233/22; C07C235/66; C07C317/28; C07C323/25; C07C323/41; C07C323/42; C07D211/46; C07D211/54; C07D213/30; A61K31/16; C07D213/32; C07D213/34; C07D213/38; C07D233/60; C07D295/12; C07D295/13; C07D295/22; C07D307/38; C07D307/42; C07D317/56; C07D333/16; C07D333/18; C07D333/28; C07D401/06; C07D401/12; C07D403/12; C07D409/04; C07D409/12; (IPC1-7): C07C235/66; C07C317/28; C07C323/25; C07C323/42; C07D213/30; C07D213/32; C07D213/34; C07D233/60; C07D295/12; C07D307/38; C07D307/42; C07D333/16; C07D333/18; C07D401/06; C07D401/12; C07D403/12; C07D409/04; C07D409/12
Domestic Patent References:
| JP6477A |
Foreign References:
| US3644518A |
Attorney, Agent or Firm:
Minoru Nakamura (6 outside)