【発明の名称】神経保護剤 - UNIVERSITY OF SOUTHAMPTON

Title:

【発明の名称】神経保護剤

Document Type and Number:

Japanese Patent JP2002508349

Kind Code:

A

Abstract:

Compounds of formula (I) wherein: Q represents an amidino group, a cyano group or a group of formula XYN-, (where X and Y are hydrogen or various groups); R^arepresents alkylene; R^band R^ceach represents alkylene, the total number of carbon atoms in said straight chains of R^band R^cbeing 7); R²and R³each represents hydrogen, or a group of formula R, RCO-, ROCO-, or RNHCO-, where R represents alkyl or aryl; the chiral carbon atom indicated by the asterisk is in the L configuration; Z is an aromatic amino acid residue; n is 0 or 1; R¹represents hydrogen, alkyl or aryl; and W represents hydrogen, alkyl or aryl; and pharmaceutically acceptable salts thereof have the ability to protect against the neuronal damage which may be caused by an ischemic event.

More Like This:

WO/1996/026711	NITRIC OXIDE SYNTHASE INHIBITORS
JP2000516204	INDUSTRIAL APPLICABILITY [Title of Invention] Useful formulation of acid addition salt chemicals
JP2009137985	DEVICE WITH COATING CONTAINING CHLORHEXIDINE GLUCONATE, COMPOSITION AND METHOD

Inventors:

Pringle, Ashley Kerr
Bradley, Mark
Sundstrom, Lars Erik
Ian Notti Faust

Application Number:

JP2000538979A

Publication Date:

March 19, 2002

Filing Date:

December 16, 1998

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIVERSITY OF SOUTHAMPTON

International Classes:

A61K31/155; A61K31/16; A61K31/165; A61K31/403; A61K31/404; A61K38/05; A61P9/00; A61P25/00; A61P43/00; C07C237/10; A61K31/4045; C07C257/14; C07C275/16; C07C279/14; C07D209/20; C07K5/078; (IPC1-7): C07C237/10; A61K31/16; A61K31/165; A61K31/4045; A61P9/00; A61P25/00; A61P43/00; C07C275/16; C07C279/14; C07D209/20

Attorney, Agent or Firm:

Soga Doteru (6 people outside)

Previous Patent: 殺菌・殺カビ性アミド

Next Patent: １−（アダマンチル）アミジンおよびグルタミン酸作動性伝達の異常と一�...