Title:
【発明の名称】新規ワクチン製剤2
Document Type and Number:
Japanese Patent JP2003500366
Kind Code:
A
Abstract:
New vaccines for use as immunotherapeutic agents in the treatment of cancer, particularly but not limited to prostate cancer, are described. The invention relates to cell co-culture techniques which leads to a significant enhancement of the phenotype of cell lines, particularly allogeneic cell lines, towards a more in vivo phenotype resulting in a vaccine reflecting a more realist phenotypic representation of an in vivo tumour. Further, the invention relates to whole cell cancer vaccines having an immunogenic component which comprises co-cultured malignant and non-malignant cells. Such vaccines produced by the various co-culture techniques described have additional advantages over single cell suspension vaccines in the mode of presentation to the immune system which leads to enhanced performance in treating the disease.
Inventors:
Andrew Sutton
Smith, peter
Stevenson, Darren
Chana, Haji
Slaves, peter
Smith, peter
Stevenson, Darren
Chana, Haji
Slaves, peter
Application Number:
JP2000619457A
Publication Date:
January 07, 2003
Filing Date:
May 19, 2000
Export Citation:
Assignee:
Onybacs Limited
International Classes:
C12N15/01; A61K35/56; A61K39/00; A61P35/00; C12N5/02; C12N5/09; C12N5/10; (IPC1-7): A61K39/00; A61P35/00; C12N5/06; C12N5/10
Attorney, Agent or Firm:
Takashi Ishida (4 others)
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