Title:
【発明の名称】19-ノルスラロイドのアルコール誘導体と有機酸との新規のエステル及びそれらの塩、それらの製造方法及びこの方法の中間体並びにそれらの薬剤としての使用
Document Type and Number:
Japanese Patent JP3056770
Kind Code:
B2
Abstract:
Products of general formula (I): in which R1 denotes an aliphatic hydrocarbon radical, R2 and R3, which are identical or different, denote a hydrogen atom or an alkyl radical, G denotes a hydrocarbon group containing from one to eighteen carbon atoms and optionally one or a number of identical or different heteroatoms, which is linked to the steroid nucleus by a carbon atom, and either X denotes XA, XA being a hydrogen atom, an alkyl radical, an arylalkyl radical or an acyl radical, and in this case Y denotes YA, YA being a group -B-O-CO-A-Z in which B denotes a saturated or unsaturated, linear or branched, divalent aliphatic radical, A denotes either a saturated or unsaturated, linear or branched, divalent aliphatic radical optionally interrupted or terminated by a divalent aromatic radical, or A denotes a divalent aromatic radical and Z denotes one of the functional groups -COOH or -SO3H, it being possible for these functional groups to be optionally converted into salt form or X denotes XB, XB being a group -CO-A-Z in which A and Z are as defined above and Y then denotes YB, YB being one of the groups chosen from -C IDENTICAL C-R4, -CH=CH-R4 or -CH2-CH2-R4, in which R4 denotes a hydrogen atom, a halogen atom, a trialkylsilyl radical, an alkyl radical or a phenyl radical, the said alkyl and phenyl radicals being optionally substituted.
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Inventors:
Martine Mogilouski
Lucian Nudelek
Francois Neek
Daniel Philibert
Lucian Nudelek
Francois Neek
Daniel Philibert
Application Number:
JP20694990A
Publication Date:
June 26, 2000
Filing Date:
August 06, 1990
Export Citation:
Assignee:
Hoechst Marion Roussel
International Classes:
A61K31/56; A61P5/24; C07J1/00; C07J3/00; C07J5/00; C07J7/00; A61K31/575; C07J9/00; C07J31/00; C07J41/00; (IPC1-7): A61K31/575; C07J3/00; C07J5/00; C07J7/00; C07J9/00
Attorney, Agent or Firm:
Motohiro Kurauchi (1 outside)