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Title:
【発明の名称】窒素含有マクロ環状リガンド及びそれらの金属複合体
Document Type and Number:
Japanese Patent JPH04506955
Kind Code:
A
Abstract:
The invention relates to ligands having the formula (I), in which X represents a heterocyclic group, together with the process for their preparation. The invention also concerns mono- or polymetallic complexes formed by said ligands with metallic ions selected from lanthanide ions, transition metal ions, barium ion, bismuth ion, lead ion and the radioisotopes 99mTc, 111In, 90Y, 64Cu and 169Yb, as well as salts physiologically acceptable to these complexes. The salts of said complexes can be used as diagnostic and therapeutic agents in magnetic resonance imaging, radiology, in vivo chemical displacement agents and in nuclear medicine.

Inventors:
Jackels, Susan Sea.
Mayer, Dominique
Application Number:
JP50580390A
Publication Date:
December 03, 1992
Filing Date:
March 23, 1990
Export Citation:
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Assignee:
Galebe Society Anonym
Wake Forest University
International Classes:
A61K49/00; A61K49/04; A61K49/06; A61K49/08; A61K51/04; C07D471/08; C07D471/18; C07D487/18; A61K51/00; C07D498/18; C07D513/18; (IPC1-7): A61K43/00; A61K49/00; A61K49/04; C07D471/08; C07D471/18; C07D487/18; C07D498/18; C07D513/18
Attorney, Agent or Firm:
Aoki Akira (3 outside)



 
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